Blog

What Is Included in a Comprehensive Metabolic Panel?

Metabolism
Man using phone to look up what is included in a comprehensive metabolic panel

Medically reviewed on June 27, 2022 by Jordan Stachel, M.S., RDN, CPT. To give you technically accurate, evidence-based information, content published on the Everlywell blog is reviewed by credentialed professionals with expertise in medical and bioscience fields.


Table of contents


Blood sample testing is an important tool for healthcare providers to evaluate and better understand aspects of your health. One of the most important of these lab tests is the comprehensive metabolic panel, also known as a CMP Test. Read on to learn more about what the panel includes below.

What Is a Comprehensive Metabolic Panel?

The comprehensive metabolic panel is a blood test that measures substances in the blood that can provide insight into metabolism and chemical balance. Metabolism is the process by which the body breaks down food and turns it into energy that the cells can easily use [1].

What Does a Comprehensive Metabolic Panel Measure?

A comprehensive metabolic panel test is relatively expansive in what it measures. It evaluates 14 different substances present in the blood. The test result includes:

  • Blood glucose level, or blood sugar, which is the body’s main source of energy
  • Calcium, an essential mineral that is needed for healthy bones and teeth, as well as the general function in the nerves, muscles, and heart
  • Electrolytes (specifically carbon dioxide, chloride, potassium, and sodium), which control the body’s pH levels, regulate hydration, and support basic nervous system functions
  • Albumin, a protein that is produced in the liver and transports nutrients throughout the body
  • Total protein, which measures the protein of albumin and globulin (an immune system factor)
  • Bilirubin, which is a waste product that naturally comes from the breakdown of proteins
  • Liver enzyme, including alkaline phosphatase (ALP), alanine transaminase (ALT), and aspartate aminotransferase (AST)
  • Blood urea, nitrogen, and creatinine, three waste products that are usually filtered out of the blood through kidney function

Any abnormal levels with any of these substances may point to serious underlying health problems [1].

Why Do You Need a Comprehensive Metabolic Panel?

Your healthcare provider may order a comprehensive metabolic panel as part of a regular checkup. Suppose you are using certain types of medication. In that case, your healthcare provider may also ask for a CMP to monitor the effectiveness of treatment and any potential side effects you may be experiencing.

If your provider believes you may have kidney or liver problems, they may order a CMP to check.

Generally, your healthcare provider can use a CMP to check for:

  • Liver and kidney function
  • Metabolism
  • pH balance
  • Glucose levels, which can help to determine potential diabetes
  • Blood proteins
  • Fluid and electrolyte balance

What to Expect

A comprehensive metabolic panel offers a simple blood draw. Your healthcare provider may ask you to fast, meaning you can’t eat or drink anything other than water. Food can cause some of the substances, like glucose, to fluctuate, which can throw off the results.

Why Are You Supposed to Fast Before a Blood Test?

Metabolic testing: what is it and how does it work?

Understanding exercise and metabolism


References

1. Comprehensive Metabolic Panel (CMP). MedlinePlus. URL. Accessed June 27, 2022.

What Does High White Blood Cell Count Mean?What Are Free T3 and T4 and How Can You Test for Them?

Get started

Latest offers

Detect early

Getting answers is in your blood. Know with Galleri multi-cancer early detection test

Learn more
Everlywell 360

83 biomarkers. One test. A lifetime of insights.

Join now
Detect early

Getting answers is in your blood. Know with Galleri multi-cancer early detection test

Learn more
Everlywell 360

83 biomarkers. One test. A lifetime of insights.

Join now

Explore Everlywell

Top picks

Shop all products

Comprehensive Food Sensitivity Test

Test your body’s IgG antibody reactivity to 204 foods

$299.00
In-person test

The Galleri® Multi-Cancer Early Detection Test

Stay ahead of cancer with the Galleri® Multi-Cancer Early Detection Test. This blood-based screening can detect a signal shared by over 50 types of cancer before symptoms appear.

$949.00
New!

Visby Rapid PCR At-Home Female STD Test

Get results in under 30 minutes with the Visby Rapid PCR At-Home Female STD Test. Designed for women, this at-home rapid PCR test detects 3 STIs with 98% accuracy.

$149.00
Shop all products