Gut & digestion tests

Food sensitivity, celiac, and colon cancer screening at home, plus allergy tests at a lab.

Shop all 8 tests

Shop gut & digestion tests

  • At-home collection

    Food Sensitivity Test

    Rated 4.69 out of 5 from 6,996 reviews

    96 foods from one finger-⁠prick card

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  • At-home collection

    Celiac Disease Screening Test

    Rated 3.80 out of 5 from 20 reviews

    tTG-⁠IgA and total IgA from a finger prick

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  • At-home collection

    FIT Colon Cancer Screening Test

    Rated 4.89 out of 5 from 212 reviews

    Hidden blood in stool, ages 45 to 75

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  • At-home collection

    Jona Gut Microbiome Test

    At-⁠home gut microbiome test

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  • In person

    Gluten Allergy (IgE)

    Gluten IgE, not a celiac test

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  • In person

    Iron & Anemia Panel

    The usual first checks for anemia, one draw

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  • In person

    Vitamin B12

    Energy and nerve vitamin, read with folate

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  • In person

    Liver panel

    The liver enzymes, proteins, and bilirubin

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Ask about gut & digestion tests

Which gut & digestion test is right for you?

Ask in your own words, and we’ll suggest where to start.

Bloating, cramps, or reactions after eating can have more than one cause. Tell me what you’ve noticed, and I’ll point you to tests that look at it.

AI-generated. For information only, not medical advice. Call 911 for an emergency.

About gut and digestion testing

  • When to consider it

    If bloating or stomach pain seems tied to what you eat, you’ve reacted to a food, celiac disease runs in your family, or you’re due for colon screening.

  • What the tests measure

    IgG food reactivity, celiac antibodies, gut microbes, and hidden blood in stool at home. At a lab, food allergy (IgE) plus liver, iron, and B12 levels.

  • At home or at a lab

    Kits use a finger prick or stool sample you mail back in a prepaid box. Lab tests, where offered, use a blood draw after a clinician reviews your request.

Common gut symptoms

How each one connects to what a test can check.

  • Bloating

    Bloating after some meals can be a reason to check IgG food reactivity or celiac antibodies.

    • Food Sensitivity Test
    • Celiac Disease Screening Test
  • Reactions soon after eating

    Hives, itching, or swelling soon after eating can signal an allergy. An allergist reads IgE.

  • Tired all the time

    Celiac can lower iron and leave you tired. Low iron has other causes a clinician can check.

  • Celiac in the family

    Close relatives of people with celiac are more likely to have it; tTG-⁠IgA is the usual check.

  • Due for colon screening

    The American Cancer Society and US Preventive Services Task Force recommend regular screening for colon cancer starting at age 45 for people at normal risk.

  • Eating mostly plants

    Plant-⁠based eating can lower vitamin B12, since it comes mostly from animal foods.

Gut health biomarkers, explained

9 biomarkers across these tests, and what each one tells you.

Why it’s checked

Results show which foods your IgG reacts to more strongly, a starting point for a talk with a clinician or dietitian.

Reading your result

Higher reactivity doesn’t mean a food is harmful or causing symptoms. Talk with a clinician before cutting foods from your diet.

Tests that include it

Why it’s checked

IgE is the antibody behind food allergies that can cause hives, swelling, or trouble breathing soon after eating.

Reading your result

A higher level means more sensitization, not a certain reaction, and a low one doesn’t clear an allergy. An allergist reads it.

Why it’s checked

Guidelines use it as the main antibody test for celiac, checked with total IgA in case your IgA runs low.

Reading your result

Eating gluten is needed for an accurate result; if you’ve stopped, ask a clinician first. A positive is usually confirmed by a specialist.

Why it’s checked

When total IgA is low, a tTG-⁠IgA result can look normal when it isn’t, so the two are checked together.

Reading your result

Low total IgA is more common in people with celiac. If yours is low, other antibody tests can be used instead.

Why it’s checked

Hidden blood can come from polyps or colorectal cancer. A positive calls for follow-⁠up with your doctor, and usually a colonoscopy. It isn’t a diagnosis.

Reading your result

A negative means no blood was found this time, not that cancer is ruled out, so FIT is repeated yearly. A positive calls for follow-⁠up with your doctor, and usually a colonoscopy.

Why it’s checked

It compares your microbiome with patterns reported in research studies. It isn’t diagnostic and doesn’t show cause.

Reading your result

An association shows similarity to a research pattern, not a condition. Talk with a clinician before acting on a result.

Good to know

A sensitivity isn’t an allergy.

  • Food sensitivity tests measure IgG. Food allergy tests measure IgE, a different antibody.
  • No single result diagnoses celiac disease or a food allergy. A clinician reads it with your history.
  • Trouble breathing or throat swelling after eating needs 911. After a serious reaction, see an allergist.

Gut health articles

All articles
  • Food allergy vs. food sensitivity: what’s the difference?

  • What is a food sensitivity?

  • Food allergy, food sensitivity, or celiac disease? How to tell them apart

Explore more categories

All tests

Questions

Common questions.

Plain answers before you order.

Hidden blood in a stool sample. It’s a screening test for adults at average risk, usually from age 45, and it doesn’t diagnose cancer. A positive result needs a colonoscopy, so talk to a clinician about any result.

Register your kit ID, collect your sample, and drop the prepaid mailer in any USPS mailbox. Results post to your account.

Yes. FSA and HSA cards are accepted at checkout. What counts as an eligible expense depends on your plan, so check with your plan administrator if you’re unsure.